Abstract
The intramuscular myxoma is a rare benign soft tissue tumor characterized by bland spindle-shaped and stellate cells embedded in hypovascular myxoid stroma. We report the isolated case of a 44-year-old female patient with an intramuscular myxoma in the anterior tibial muscle and report the clinical and radiographic findings. We performed an analysis of the GNAS gene mutation status with a positive finding. In difficult cases, recurrent tumors or small biopsies detection of a GNAS mutation can be useful to confirm the diagnosis of an intramuscular myxoma.
MeSH terms
-
Adult
-
Antigens, CD34 / genetics
-
Chromogranins
-
DNA Mutational Analysis
-
Diagnosis, Differential
-
Female
-
GTP-Binding Protein alpha Subunits, Gs / genetics
-
Humans
-
Incidental Findings
-
Magnetic Resonance Imaging
-
Muscle Neoplasms / diagnosis
-
Muscle Neoplasms / genetics
-
Muscle Neoplasms / pathology*
-
Muscle Neoplasms / surgery
-
Muscle, Skeletal / pathology*
-
Muscle, Skeletal / surgery
-
Myxoma / diagnosis
-
Myxoma / genetics
-
Myxoma / pathology*
-
Myxoma / surgery
-
Vimentin / genetics
Substances
-
Antigens, CD34
-
Chromogranins
-
Vimentin
-
GNAS protein, human
-
GTP-Binding Protein alpha Subunits, Gs