G × E interaction and neurodevelopment I. Focus on maltreatment

Epidemiol Psychiatr Sci. 2012 Dec;21(4):347-51. doi: 10.1017/S2045796012000418.

Abstract

In a short series of articles, we will review the evidence for genotype by environment interaction (G × E) in developmental psychopathology. We will focus specifically on the characteristics of types of exposure assessed with respect to both their methods and findings. This article aims to review the studies exploring the effects of child maltreatment on children, adolescents and young adults closer in time to maltreatment experience, in a G × E perspective.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adolescent Development
  • Brain / growth & development
  • Brain-Derived Neurotrophic Factor / genetics
  • Child
  • Child Abuse / psychology*
  • Child Development
  • Gene-Environment Interaction
  • Genotype
  • Humans
  • Mental Disorders* / etiology
  • Mental Disorders* / genetics
  • Mental Disorders* / psychology
  • Monoamine Oxidase / genetics
  • Polymorphism, Genetic
  • Receptors, Corticotropin-Releasing Hormone / genetics
  • Serotonin Plasma Membrane Transport Proteins / genetics
  • Young Adult

Substances

  • Brain-Derived Neurotrophic Factor
  • Receptors, Corticotropin-Releasing Hormone
  • SLC6A4 protein, human
  • Serotonin Plasma Membrane Transport Proteins
  • CRF receptor type 1
  • Monoamine Oxidase