Azygous anterior cerebral artery and associated aneurysms: detection and identification using 3-dimensional time-of-flight magnetic resonance angiography

J Neuroimaging. 2014 Jan-Feb;24(1):18-22. doi: 10.1111/j.1552-6569.2012.00769.x. Epub 2012 Nov 19.

Abstract

Aim: The azygous anterior cerebral artery (Az) is a rarely observed anomaly of the anterior cerebral artery, and its associated aneurysm is even rarer. Our aim was to evaluate 3-dimensional time-of-flight magnetic resonance angiography (3-D-TOF MRA) in the diagnosis of Az and associated aneurysms.

Materials and methods: Three thousand five hundred seventy-two consecutive patients underwent 3-D-TOF MRA at 3.0 T. Postprocessing techniques, including volume rendering (VR) and single artery highlighting, were performed by a 3-D specialist. All MRA data and clinical information were recorded and stored in a database for further analysis.

Results: Fourteen patients (.39%) were identified as having an Az. Among these cases, 3 males (21.43%) had an aneurysm located at the distal bifurcation of the Az, with a mean size of 9.43 ± 3.33 mm. In MRA, the common trunk of the Az was slightly larger in diameter than the A1 segment (2.62 ± .35 mm vs. 2.54 ± .35 mm; P = .008).

Conclusions: With the VR technique, 3-D-TOF MRA is feasible and valuable in detecting an Az and associated aneurysm. Our MRA-based study has proved that the Az is a rare anomaly but has a relatively high incidence of associated aneurysms.

Keywords: Azygous anterior cerebral artery; intracranial aneurysm; magnetic resonance angiography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cerebral Arteries / abnormalities*
  • Cerebral Arteries / pathology*
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Intracranial Aneurysm / etiology*
  • Intracranial Aneurysm / pathology*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Middle Aged
  • Observer Variation
  • Reproducibility of Results
  • Sensitivity and Specificity