Emerging noninvasive biomarkers for early detection of Alzheimer's disease

Arch Med Res. 2012 Nov;43(8):663-6. doi: 10.1016/j.arcmed.2012.10.013. Epub 2012 Nov 7.

Abstract

Alzheimer's disease (AD) diagnosis still depends on the triad of clinical, imaging and neuropsychological testing. The development of accurate, easy to use and inexpensive biological markers for AD is a long-standing aspiration for researchers and the medical community. Here we describe some of the recent advances in the field of biomarkers, both in cerebrospinal fluid (CSF) and in peripheral blood.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alzheimer Disease / blood
  • Alzheimer Disease / cerebrospinal fluid
  • Alzheimer Disease / diagnosis*
  • Biomarkers / blood
  • Biomarkers / cerebrospinal fluid
  • Blood Platelets / metabolism
  • Early Diagnosis*
  • Humans
  • Sensitivity and Specificity
  • tau Proteins / blood

Substances

  • Biomarkers
  • tau Proteins