Unambiguous structure elucidation of heterocyclic products from condensation-cyclisation reactions of enaminones by 2D INADEQUATE and 15N NMR

Abstract

The reaction of enaminones with 3-amino-2-cyanopent-2-enedinitrile can lead to an array of 12 possible products, depending on the reaction pathway and tautomerization. The use of 2D INADEQUATE and (15)N NMR for the unambiguous structure elucidation of the reaction products is discussed in this manuscript.