Growth inhibition of Streptococcus from the oral cavity by α-amyrin esters

Molecules. 2012 Oct 25;17(11):12603-11. doi: 10.3390/molecules171112603.

Abstract

Five terpenoids were tested by the macrodilution broth method to determine their inhibition activity on cariogenic bacterial growth. In general, α-, β-amyrin and α-amyrin phenylacetate proved to be active, reducing the bacterial viability to less than 20%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / pharmacology*
  • Dental Caries / microbiology
  • Esterification
  • Esters
  • Humans
  • Microbial Viability / drug effects
  • Mouth / microbiology*
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemical synthesis
  • Oleanolic Acid / pharmacology*
  • Streptococcus / drug effects*
  • Streptococcus / growth & development

Substances

  • Anti-Bacterial Agents
  • Esters
  • Oleanolic Acid