Fatal respiratory infections associated with rhinovirus outbreak, Vietnam

Emerg Infect Dis. 2012 Nov;18(11):1886-8. doi: 10.3201/eid1811.120607.

Abstract

During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. Human rhinovirus is an underappreciated cause of severe pneumonia in vulnerable groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5' Untranslated Regions
  • Disease Outbreaks*
  • Female
  • Genome, Viral
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Phylogeny
  • Picornaviridae Infections / epidemiology*
  • Picornaviridae Infections / mortality*
  • Respiratory Tract Infections / epidemiology*
  • Respiratory Tract Infections / mortality*
  • Respiratory Tract Infections / virology
  • Rhinovirus / classification
  • Rhinovirus / genetics*
  • Serotyping
  • Vietnam / epidemiology

Substances

  • 5' Untranslated Regions