Susceptibility of children to sapovirus infections, Nicaragua, 2005-2006

Emerg Infect Dis. 2012 Nov;18(11):1875-8. doi: 10.3201/eid1811.111581.

Abstract

We describe the genetic diversity of sapovirus (SaV) in children in Nicaragua and investigate the role of host genetic factors and susceptibility to SaV infections. Our results indicate that neither ABO blood group, Lewis phenotype, nor secretor status affects susceptibility to SaV infection in Nicaragua.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ABO Blood-Group System / genetics
  • Caliciviridae Infections / genetics*
  • Caliciviridae Infections / virology*
  • Capsid Proteins / genetics
  • Child, Preschool
  • Fucosyltransferases / genetics
  • Galactoside 2-alpha-L-fucosyltransferase
  • Gastroenteritis / genetics*
  • Gastroenteritis / virology*
  • Genetic Predisposition to Disease*
  • Genetic Variation
  • Genotype
  • Humans
  • Infant
  • Nicaragua
  • Phylogeny
  • Polymorphism, Single Nucleotide
  • Sapovirus / classification
  • Sapovirus / genetics*

Substances

  • ABO Blood-Group System
  • Capsid Proteins
  • Fucosyltransferases