Striking similarity: GATA-3 regulates ILC2 and Th2 cells

Liang Zhou

doi:10.1016/j.immuni.2012.10.002

Striking similarity: GATA-3 regulates ILC2 and Th2 cells

Immunity. 2012 Oct 19;37(4):589-91. doi: 10.1016/j.immuni.2012.10.002.

Author

Liang Zhou¹

Affiliation

¹ Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. l-zhou@northwestern.edu

Abstract

Innate lymphoid cells (ILCs) and T helper (Th) cells share similar effector functions. In this issue of Immunity, Hoyler et al. (2012) and Mjosberg et al. (2012) demonstrate that GATA-3, a Th2 regulator, controls ILC2 differentiation, maintenance, and function.

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