Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series

Abstract

Angiocentric glioma (AG) is a rare, epilepsy-associated, low-grade neoplasm with a characteristic perivascular growth pattern. Here, we review the histological types, surgical interventions, and postoperative seizure in our three cases of AG with drug-resistant epilepsy. Some patients with AG present focal cortical dysplasia. For these patients, extended lesionectomy including the adjacent cortical dysplasia is necessary to achieve a seizure-free outcome. Surgical planning based on comprehensive evaluation of epilepsy and cortical dysplasia is therefore an important step for all patients.