Abstract
Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger.
Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aspergillus niger / genetics
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Aspergillus niger / growth & development
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Aspergillus niger / metabolism*
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Chromosome Mapping
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Chromosomes, Fungal / genetics
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Fungal Proteins / genetics
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Fungal Proteins / metabolism*
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Galactose / metabolism*
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Gene Expression Profiling
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Gene Expression Regulation, Fungal
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Metabolic Networks and Pathways*
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Mutation
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Oligonucleotide Array Sequence Analysis
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Oligosaccharides / metabolism
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Oxidation-Reduction
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Polysaccharides / metabolism
Substances
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Fungal Proteins
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Oligosaccharides
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Polysaccharides
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Galactose