GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger

FEBS Lett. 2012 Nov 16;586(22):3980-5. doi: 10.1016/j.febslet.2012.09.029. Epub 2012 Oct 12.

Abstract

Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aspergillus niger / genetics
  • Aspergillus niger / growth & development
  • Aspergillus niger / metabolism*
  • Chromosome Mapping
  • Chromosomes, Fungal / genetics
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism*
  • Galactose / metabolism*
  • Gene Expression Profiling
  • Gene Expression Regulation, Fungal
  • Metabolic Networks and Pathways*
  • Mutation
  • Oligonucleotide Array Sequence Analysis
  • Oligosaccharides / metabolism
  • Oxidation-Reduction
  • Polysaccharides / metabolism

Substances

  • Fungal Proteins
  • Oligosaccharides
  • Polysaccharides
  • Galactose

Associated data

  • GEO/GSE40219