Ethnicity and psychiatric comorbidity in a national sample: evidence for latent comorbidity factor invariance and connections with disorder prevalence

Soc Psychiatry Psychiatr Epidemiol. 2013 May;48(5):701-10. doi: 10.1007/s00127-012-0595-5. Epub 2012 Sep 30.

Abstract

Purpose: Prevalence rates, and bivariate comorbidity patterns, of many common mental disorders differ significantly across ethnic groups. While studies have examined multivariate comorbidity patterns by gender and age, no studies to our knowledge have examined such patterns by ethnicity. Such an investigation could aid in understanding the nature of ethnicity-related health disparities in mental health and is timely given the likely implementation of multivariate comorbidity structures (i.e., internalizing and externalizing) to frame key parts of DSM-5.

Methods: We investigated whether multivariate comorbidity of 11 common mental disorders, and their associated latent comorbidity factors, differed across five ethnic groups in a large, nationally representative sample (n = 43,093). We conducted confirmatory factor analyses and factorial invariance analyses in White (n = 24,507), Hispanic/Latino (n = 8,308), Black (n = 8,245), Asian/Pacific Islander (n = 1,332), and American Indian/Alaska Native (n = 701) individuals.

Results: Results supported a two-factor internalizing-externalizing comorbidity factor model in both lifetime and 12-month diagnoses. This structure was invariant across ethnicity, but factor means differed significantly across ethnic groups.

Conclusions: These findings, taken together, indicated that observed prevalence rate differences between ethnic groups reflect ethnic differences in latent internalizing and externalizing factor means. We discuss implications for classification (DSM-5 and ICD-11 meta-structure), health disparities research, and treatment.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Comorbidity*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Ethnicity / psychology
  • Ethnicity / statistics & numerical data*
  • Factor Analysis, Statistical
  • Female
  • Healthcare Disparities / ethnology*
  • Healthcare Disparities / statistics & numerical data
  • Humans
  • Internal-External Control
  • International Classification of Diseases
  • Male
  • Mental Disorders / classification
  • Mental Disorders / diagnosis
  • Mental Disorders / ethnology*
  • Middle Aged
  • Models, Psychological
  • Multivariate Analysis
  • Prevalence
  • United States / epidemiology
  • Young Adult