Prevalence of essential tremor in urban Lagos, Nigeria: a door-to-door community-based study

BMC Neurol. 2012 Sep 27:12:110. doi: 10.1186/1471-2377-12-110.

Abstract

Background: Essential tremor (ET) is one of the commonest movement disorders though the prevalence varies globally. There is paucity of data on ET prevalence in sub-Saharan Africa. The study aimed to determine the prevalence of ET in a Nigerian community.

Methods: This door-to-door survey was conducted in two stages. In Stage 1, 3000 randomly selected residents of an urban centre in Lagos, Nigeria, were screened using a questionnaire to detect symptoms of movement disorder. 234 participants who responded positively regarding presence of tremors were rescreened using an ET-specific questionnaire, a face-to-face interview and neurological examination. Diagnosis of ET was based on the Movement Disorders Society (MDS) consensus diagnostic criteria for ET.

Results: Of the 3000 participants, forty responded positively to the ET screening questionnaire, of which 36 (19 females and 17 males) had a final diagnosis of ET, giving a crude prevalence of 12 per 1000 (95% CI = 8.1- 15.9). Gender specific prevalence was 10.3 /1000 in males and 14.3/1000 in females. Age specific prevalence increased with advancing age in both sexes. Age adjusted prevalence (WHO New world population) was 23.8 per 1000.

Conclusions: We documented a high prevalence of ET in this study, with typical increasing prevalence with advancing age as previously reported in other populations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  • Data Collection*
  • Essential Tremor / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nigeria / epidemiology
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Urban Population / statistics & numerical data*
  • Young Adult