Compliance to micronutrient supplementation in children 3 to 24 months of age from a semi-rural community in Mexico

Salud Publica Mex. 2012 Oct;54(5):470-8. doi: 10.1590/s0036-36342012000500003.

Abstract

Objective: To identify associated factors to compliance for multiple micronutrient (MM) or iron and vitamin A (IVITA) supplementation, in children (3 to 24 months old).

Materials and methods: A database (n=465 children) from a randomized, controlled, clinical trial, carried out in a semi-rural setting in Mexico, was analyzed. The compliance rate of MM and IVITA supplements was calculated. Adequate compliance rate (AC>80%), and its association with children and households characteristics, was determined.

Results: The compliance mean was high (MM:78.2%, IVITA:80.1%; p<0.05). The odds of AC were 59% greater in the children of IVITA than with MM group, although the estimate was only marginally significant (p=0.052). Maternal education (p<0.001), child birth weight (p=0.003), and children with cough (p<0.001) or fever (p=0.024) were significantly associated with AC and significantly marginal was maternal indigenous (p=0.071).

Conclusion: The high AC was consistent with others efficacy studies. More research is needed to document physiological, cultural, social and operative factors affecting compliance with supplementation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Birth Weight
  • Breast Feeding
  • Cough / epidemiology
  • Databases, Factual / statistics & numerical data
  • Diarrhea / epidemiology
  • Dietary Supplements*
  • Double-Blind Method
  • Educational Status
  • Female
  • Fever / epidemiology
  • Hemoglobins / analysis
  • Humans
  • Indians, North American / statistics & numerical data
  • Infant
  • Infant Food
  • Iron / administration & dosage
  • Male
  • Medication Adherence / ethnology
  • Medication Adherence / statistics & numerical data*
  • Mexico
  • Micronutrients / administration & dosage*
  • Mothers / statistics & numerical data
  • Randomized Controlled Trials as Topic / statistics & numerical data
  • Risk Factors
  • Rural Population / statistics & numerical data
  • Socioeconomic Factors
  • Vitamin A / administration & dosage

Substances

  • Hemoglobins
  • Micronutrients
  • Vitamin A
  • Iron