Chiral imidate-ferrocenylphosphanes: synthesis and application as P,N-ligands in iridium(I)-catalyzed hydrogenation of unfunctionalized and poorly functionalized olefins

Katrien Bert; Timothy Noël; Wim Kimpe; Jan L Goeman; Johan Van der Eycken

doi:10.1039/c2ob25871d

Chiral imidate-ferrocenylphosphanes: synthesis and application as P,N-ligands in iridium(I)-catalyzed hydrogenation of unfunctionalized and poorly functionalized olefins

Org Biomol Chem. 2012 Nov 14;10(42):8539-50. doi: 10.1039/c2ob25871d. Epub 2012 Sep 26.

Authors

Katrien Bert¹, Timothy Noël, Wim Kimpe, Jan L Goeman, Johan Van der Eycken

Affiliation

¹ Laboratory for Organic and Bioorganic Synthesis, Department of Organic Chemistry, Ghent University, Krijgslaan 281 (S.4), B-9000 Ghent, Belgium.

PMID: 23011476
DOI: 10.1039/c2ob25871d

Abstract

A small library of chiral imidate-ferrocenylphosphane ligands was efficiently synthesized (8 examples) and evaluated in the iridium(I)-catalyzed hydrogenation of unfunctionalized and poorly functionalized olefins. These catalysts perform very well in a range of examples (yields and ee's up to 100%).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemistry*
Catalysis
Ferrous Compounds / chemical synthesis
Ferrous Compounds / chemistry*
Hydrogenation
Imidoesters / chemical synthesis
Imidoesters / chemistry*
Iridium / chemistry*
Ligands
Metallocenes
Phosphines / chemical synthesis
Phosphines / chemistry*

Substances

Alkenes
Ferrous Compounds
Imidoesters
Ligands
Metallocenes
Phosphines
Iridium
phosphine
ferrocene