Dermoscopy of discoid lupus erythematosus

Br J Dermatol. 2013 Feb;168(2):284-8. doi: 10.1111/bjd.12044. Epub 2012 Nov 20.

Abstract

Background: Dermoscopy is useful in evaluating skin tumours, but its applicability also extends into the field of inflammatory skin disorders. Discoid lupus erythematosus (DLE) represents the most common subtype of cutaneous lupus erythematosus. While dermoscopy and videodermoscopy have been shown to aid the differentiation of scalp DLE from other causes of scarring alopecia, limited data exist concerning dermoscopic criteria of DLE in other locations, such as the face, trunk and extremities.

Objective: To describe the dermoscopic criteria observed in a series of patients with DLE located on areas other than the scalp, and to correlate them to the underlying histopathological alterations.

Methods: DLE lesions located on the face, trunk and extremities were dermoscopically and histopathologically examined. Selection of the dermoscopic variables included in the evaluation process was based on data in the available literature on DLE of the scalp and on our preliminary observations. Analysis of data was done with SPSS analysis software.

Results: Fifty-five lesions from 37 patients with DLE were included in the study. Perifollicular whitish halo, follicular keratotic plugs and telangiectasias were the most common dermoscopic criteria. Statistical analysis revealed excellent correlation between dermoscopic and histopathological findings. Notably, a time-related alteration of dermoscopic features was observed.

Conclusions: The present study provides new insights into the dermoscopic variability of DLE located on the face, trunk and extremities.

Publication types

  • Evaluation Study
  • Multicenter Study

MeSH terms

  • Adult
  • Dermoscopy*
  • Female
  • Humans
  • Lupus Erythematosus, Discoid / pathology*
  • Male
  • Observer Variation
  • Prospective Studies
  • Time Factors