A novel methylated sesquiterpene from seagrass Posidonia oceanica (L.) Delile

Nat Prod Res. 2013;27(14):1265-70. doi: 10.1080/14786419.2012.725401. Epub 2012 Sep 17.

Abstract

Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has been established on the basis of 1D- and 2D-NMR spectroscopy, GS/MS and ES mass spectrometry. Antibacterial effects of crude extracts from P. oceanica were evaluated against: Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus microorganisms.

MeSH terms

  • Alismatales / chemistry*
  • Chloroform
  • Chromatography, Thin Layer
  • Colony Count, Microbial
  • Disk Diffusion Antimicrobial Tests
  • Escherichia coli / drug effects
  • Fatty Acids / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Methylation
  • Micrococcus luteus / drug effects
  • Molecular Structure
  • Plant Extracts / chemistry*
  • Plant Leaves / chemistry*
  • Pseudomonas aeruginosa / drug effects
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology
  • Sitosterols / isolation & purification
  • Staphylococcus / drug effects

Substances

  • Fatty Acids
  • Plant Extracts
  • Sesquiterpenes
  • Sitosterols
  • gamma-sitosterol
  • Chloroform