Besides CYP2C19, PON1 genetic variant influences post-clopidogrel platelet reactivity in Chinese patients

Int J Cardiol. 2013 Apr 30;165(1):204-6. doi: 10.1016/j.ijcard.2012.08.017. Epub 2012 Sep 11.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Coronary Syndrome / drug therapy
  • Acute Coronary Syndrome / genetics
  • Acute Coronary Syndrome / metabolism
  • Aged
  • Alleles
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Aryldialkylphosphatase / genetics*
  • Asian People / genetics*
  • Blood Platelets / drug effects
  • Blood Platelets / metabolism*
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Female
  • Genetic Variation / genetics*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / pharmacology
  • Ticlopidine / therapeutic use

Substances

  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Aryldialkylphosphatase
  • PON1 protein, human
  • Ticlopidine