New kaurene diterpenoid glycosides from fenugreek seeds

Nat Prod Res. 2013;27(13):1202-7. doi: 10.1080/14786419.2012.722087. Epub 2012 Sep 6.

Abstract

Two new kaurene diterpenoid glycosides, named Graecumoside A (1) and B (2), were isolated from fenugreek seeds, along with three known flavonoid-C-glycosides, isoorientin (3), isovitexin (4) and vitexin (5). By combined analyses of 1D- and 2D-NMR, and MS spectroscopy, the structures of two new compounds were elucidated as 3-O-β- D-glucopyranosyl kaur-5, 16-dien-3β, 6, 13β-trihydroxy-7-oxo-18-oic acid methyl ester and 3-O-β-neohesperidosyl kaur-5, 16-dien-3β, 6, 13β-trihydroxy-7-oxo-18-oic acid methyl ester, respectively. The kaurene diterpenoid glycosides were first isolated and identified from fenugreek seeds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diterpenes / chemistry*
  • Glycosides / chemistry*
  • Molecular Structure
  • Seeds / chemistry*
  • Trigonella / chemistry*

Substances

  • Diterpenes
  • Glycosides