The double-edged sword of CRISPR-Cas systems

Cell Res. 2013 Jan;23(1):15-7. doi: 10.1038/cr.2012.124. Epub 2012 Sep 4.

Abstract

A recent paper gives the details on how specific small RNAs can program a protein to cleave an undesired piece of DNA and to provide immunity to a microbial cell.

MeSH terms

  • Bacteria / genetics
  • Bacteria / metabolism
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Genetic Loci*
  • Genome, Bacterial
  • RNA, Small Untranslated / genetics
  • RNA, Small Untranslated / metabolism
  • Streptococcus thermophilus / genetics
  • Streptococcus thermophilus / metabolism

Substances

  • Bacterial Proteins
  • RNA, Small Untranslated