Juvenile chronic myelogenous leukemia with abnormalities of chromosomes 4 and 5

S L Berg; C K Phebus; S L Wenger

doi:10.1016/0165-4608(90)90197-i

Juvenile chronic myelogenous leukemia with abnormalities of chromosomes 4 and 5

Cancer Genet Cytogenet. 1990 Jan;44(1):55-9. doi: 10.1016/0165-4608(90)90197-i.

Authors

S L Berg¹, C K Phebus, S L Wenger

Affiliation

¹ Division of Hematology/Oncology, University of Pittsburgh, School of Medicine, Pennsylvania.

PMID: 2293880
DOI: 10.1016/0165-4608(90)90197-i

Abstract

A case of a boy with juvenile chronic myelogenous leukemia (CML) and independent clonal abnormalities of chromosomes 4 and 5 is presented. The characteristics and cytogenetics of CML are discussed, as is the involvement of chromosomes 4 and 5 in hematologic malignancies. The significance of these karyotypic findings in juvenile CML is explored.

MeSH terms

Child, Preschool
Chromosome Banding
Chromosome Deletion*
Chromosomes, Human, Pair 4*
Chromosomes, Human, Pair 5*
Female
Genetic Markers
Humans
Karyotyping
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Male

Substances

Genetic Markers