Haemorrhage due to proteolysis of FXIII and hyperfibrinolysis under vemurafenib treatment of metastatic melanoma

MeSH terms

• Antineoplastic Agents / administration & dosage
• Antineoplastic Agents / adverse effects*
• Factor XIII / metabolism
• Female
• Fibrinolysis / drug effects
• Hemorrhage / blood
• Hemorrhage / chemically induced*
• Humans
• Indoles / administration & dosage
• Indoles / adverse effects*
• Male
• Melanoma / drug therapy*
• Melanoma / secondary*
• Protein Kinase Inhibitors / administration & dosage
• Protein Kinase Inhibitors / adverse effects*
• Proteolysis / drug effects
• Proto-Oncogene Proteins B-raf / antagonists & inhibitors
• Sulfonamides / administration & dosage
• Sulfonamides / adverse effects*
• Vemurafenib