Celiac disease

Gastroenterol Clin North Am. 2012 Sep;41(3):639-50. doi: 10.1016/j.gtc.2012.06.004. Epub 2012 Jul 4.

Abstract

Celiac disease is common, affecting approximately 1 in 100 people, yet it remains underdiagnosed. This article reviews our current understanding of celiac disease, diagnosis, and common pitfalls. Although the cornerstone of treatment is a gluten-free diet, some patients may still have persisting symptoms and warrant further investigations.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Atrophy
  • Autoantibodies / blood
  • Biopsy
  • Celiac Disease / diagnosis*
  • Celiac Disease / diet therapy*
  • Colitis, Microscopic / complications
  • Diarrhea / etiology
  • Diet, Gluten-Free
  • Duodenum / pathology
  • HLA-DQ Antigens / immunology
  • Humans
  • Immunoglobulin A / immunology
  • Inflammatory Bowel Diseases / complications
  • Microvilli / pathology
  • Patient Compliance
  • Recurrence
  • Transglutaminases / immunology

Substances

  • Autoantibodies
  • HLA-DQ Antigens
  • HLA-DQ2 antigen
  • HLA-DQ8 antigen
  • Immunoglobulin A
  • Transglutaminases