Abstract
The synthesis of quaternary imidazolium chlorides was performed by reaction of 1-n-hexyl-2-phenyl-imidazole with chloromethylalkyl ether or chlormethylalkyl sulfide. The antibacterial properties of the compounds obtained was tested on 13 strains of bacteria and fungi. Chlorides with octyl- and decylthiomethyl moiety indicated the best antibacterial activity.
MeSH terms
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Anti-Bacterial Agents
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Anti-Infective Agents / chemical synthesis*
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Anti-Infective Agents / pharmacology
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / pharmacology
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Bacteria / drug effects
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Chromatography, High Pressure Liquid
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Fungi / drug effects
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Imidazoles / chemical synthesis*
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Imidazoles / pharmacology
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Microbial Sensitivity Tests
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Sulfides / chemical synthesis
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Sulfides / pharmacology
Substances
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Anti-Bacterial Agents
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Anti-Infective Agents
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Antifungal Agents
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Imidazoles
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Sulfides