Third-generation cephalosporin-resistant Vibrio cholerae, India

Emerg Infect Dis. 2012 Aug;18(8):1326-8. doi: 10.3201/eid1808.111686.

Abstract

Vibrio cholerae resistance to third-generation cephalosporins is rarely reported. We detected a strain that was negative for extended-spectrum β-lactamase and positive for the AmpC disk test, modified Hodge test, and EDTA disk synergy test and harbored the blaDHA-1 and blaNDM-1 genes. The antimicrobial drug susceptibility profile of V. cholerae should be monitored.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / biosynthesis
  • Bacterial Proteins / genetics*
  • Cephalosporin Resistance / genetics*
  • Cephalosporins / pharmacology*
  • Child, Preschool
  • Cholera / epidemiology*
  • Cholera / microbiology
  • Genotype
  • Humans
  • India / epidemiology
  • Microbial Sensitivity Tests
  • Vibrio cholerae O1 / drug effects*
  • Vibrio cholerae O1 / enzymology
  • Vibrio cholerae O1 / genetics
  • Vibrio cholerae O1 / isolation & purification
  • beta-Lactamases / biosynthesis
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Cephalosporins
  • AmpC beta-lactamases
  • beta-Lactamases
  • carbapenemase