Two new compounds isolated from Liriope muscari

Molecules. 2012 Jul 25;17(8):8773-81. doi: 10.3390/molecules17088773.

Abstract

Two new compounds, (2S,3R)-methyl 7-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-carboxylate (1) and (4R,5S)-5-(3-hydroxy-2,6-dimethylphenyl)-4-isopropyldihydrofuran-2-one (2), tentatively named norcurlignan and limlactone, respectively, were isolated from Liriope muscari, together with the known compound (-)-pinoresinol (3). The structures of these compounds were elucidated and characterized on the basis of 1D NMR, 2D NMR, CD and MS data. The in vitro antioxidant activities of compounds 1-3 were assessed by the DPPH and ABTS scavenging methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzofurans / chemistry
  • Benzofurans / isolation & purification*
  • Benzothiazoles / chemistry
  • Biphenyl Compounds / chemistry
  • Chromatography, Gel
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radicals / chemistry
  • Furans / chemistry
  • Furans / isolation & purification
  • Lignans / chemistry
  • Lignans / isolation & purification
  • Liriope Plant / chemistry*
  • Magnetic Resonance Spectroscopy
  • Medicine, Chinese Traditional
  • Molecular Conformation
  • Molecular Structure
  • Picrates / chemistry
  • Sulfonic Acids / chemistry

Substances

  • (2S,3R)-methyl 7-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-3-(hydroxymethyl)-2,3-dihydrobenzofuran-5-carboxylate
  • (4R,5S)-5-(3-hydroxy-2,6-dimethylphenyl)-4-isopropyldihydrofuran-2-one
  • Benzofurans
  • Benzothiazoles
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Free Radicals
  • Furans
  • Lignans
  • Picrates
  • Sulfonic Acids
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • 1,1-diphenyl-2-picrylhydrazyl
  • pinoresinol