[Update on current care guidelines: ovarian cancer]

Duodecim. 2012;128(12):1300-1.
[Article in Finnish]

Abstract

Ovarian cancer is the most lethal gynaecological cancer. It appears that seemingly ovarian or primary peritoneal carcinomas, in fact, originate from fimbriae. BRCA1/2 mutation carriers are recommended for the removal of ovaries and fimbriae, to reduce the risk of cancer. Treatment of epithelial ovarian cancer is based on the combination of surgery and chemotherapy. The residual tumour volume at the primary operation is the most important predictive factor of survival. The best response at the primary treatment is observed with combination chemotherapy with taxane and platinum. Adding bevacitzumab to first line chemotherapy may improve survival.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antibodies, Monoclonal, Humanized / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bevacizumab
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Female
  • Humans
  • Neoplasm, Residual / drug therapy
  • Neoplasm, Residual / surgery
  • Ovarian Neoplasms / drug therapy*
  • Ovarian Neoplasms / surgery*
  • Practice Guidelines as Topic
  • Survival Analysis
  • Taxoids / administration & dosage

Substances

  • Antibodies, Monoclonal, Humanized
  • Taxoids
  • Bevacizumab
  • Cisplatin