Antibacterial secondary metabolites from the cave sponge Xestospongia sp

Sridevi Ankisetty; Marc Slattery

doi:10.3390/md10051037

Antibacterial secondary metabolites from the cave sponge Xestospongia sp

Mar Drugs. 2012 May;10(5):1037-1043. doi: 10.3390/md10051037. Epub 2012 May 7.

Authors

Sridevi Ankisetty¹, Marc Slattery¹

Affiliation

¹ Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

Abstract

Chemical investigation of the cave sponge Xestospongia sp. resulted in the isolation of three new polyacetylenic long chain compounds along with two known metabolites. The structures of the new metabolites were established by NMR and MS analyses. The antibacterial activity of the new metabolites was also evaluated.

Keywords: Xestospongia; antibacterial activity; polyacetylenes.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects
Magnetic Resonance Spectroscopy / methods
Mass Spectrometry / methods
Xestospongia / chemistry*
Xestospongia / metabolism

Substances

Anti-Bacterial Agents