Exploring the pharmacology and action spectra of photochromic open-channel blockers

Chembiochem. 2012 Aug 13;13(12):1746-9. doi: 10.1002/cbic.201200216. Epub 2012 Jul 13.

Authors

Timm Fehrentz¹, Christian A Kuttruff, Florian M E Huber, Michael A Kienzler, Peter Mayer, Dirk Trauner

Affiliation

¹ Department of Chemistry, University of Munich and Center for Integrated Protein Science-CIPSM, Butenandtstrasse 5-13, 81377 Munich, Germany.

PMID: 22807111
DOI: 10.1002/cbic.201200216

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aniline Compounds / chemistry*
Animals
Humans
Light
Mice
Models, Molecular
Patch-Clamp Techniques
Photochemical Processes
Potassium Channel Blockers / chemical synthesis*
Potassium Channel Blockers / pharmacology
Quaternary Ammonium Compounds / chemistry*
Shaker Superfamily of Potassium Channels / antagonists & inhibitors
Shaker Superfamily of Potassium Channels / metabolism
Voltage-Gated Sodium Channel Blockers / chemical synthesis*
Voltage-Gated Sodium Channel Blockers / pharmacology
Voltage-Gated Sodium Channels / metabolism

Substances

Aniline Compounds
Potassium Channel Blockers
Quaternary Ammonium Compounds
Shaker Superfamily of Potassium Channels
Voltage-Gated Sodium Channel Blockers
Voltage-Gated Sodium Channels