Effects of terahertz radiation at atmospheric oxygen frequency of 129 GHz on blood nitrite concentrations under conditions of different types of stress against the background of administration of nonselective inhibitor of constitutive NO-synthases
Bull Exp Biol Med. 2012 Feb;152(4):435-8.
doi: 10.1007/s10517-012-1547-5.
[Article in
English,
Russian]
Affiliation
- 1 V. I. Razumovskii Saratov State Medical University, Ministry of Health Care and Social Development of the Russian Federation. Russia.
Abstract
We studied the effect of terahertz radiation at atmospheric oxygen frequency 129 GHz on blood nitrite concentration in different types of experimental stress against the background of administration of nonselective inhibitor of constitutive NO-synthases. Normalizing effects of radiation on blood nitrite dynamics in animals with acute stress was shown after 15-min exposure and in animals with chronic stress after 30-min exposure. No positive effect of terahertz radiation was observed on altered blood nitrite concentration in male rats after preliminary administration of nonselective constitutive NO-synthase isoform inhibitor L-NAME.
MeSH terms
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Animals
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Enzyme Inhibitors / pharmacology
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Immobilization
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Injections, Intramuscular
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Male
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NG-Nitroarginine Methyl Ester / pharmacology
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Nitric Oxide / antagonists & inhibitors
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Nitric Oxide / metabolism
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Nitric Oxide Synthase Type III / antagonists & inhibitors
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Nitric Oxide Synthase Type III / metabolism*
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Nitrites / blood*
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Oxygen / chemistry
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Rats
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Stress, Physiological / drug effects
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Stress, Physiological / radiation effects*
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Terahertz Radiation
Substances
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Enzyme Inhibitors
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Nitrites
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Nitric Oxide
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Nitric Oxide Synthase Type III
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Oxygen
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NG-Nitroarginine Methyl Ester