Abstract
The ephedrine-based diselenide appears as a new promiscuous catalyst, able to generate optically active alcohols by addition of organozinc to aldehydes (up to 97% ee), and shows powerful GPx like activity, reducing H(2)O(2) to water in only 16.33 min (eleven times faster than PhSeSePh).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Drug Design
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Ephedrine / chemistry*
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Glutathione Peroxidase / chemistry*
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Glutathione Peroxidase / metabolism
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Molecular Mimicry*
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Organoselenium Compounds / chemistry*
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Stereoisomerism
Substances
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Organoselenium Compounds
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Glutathione Peroxidase
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Ephedrine