Venous hemangioma of the posterior mediastinum

Ann Thorac Cardiovasc Surg. 2012;18(3):247-50. doi: 10.5761/atcs.cr.11.01706.

Abstract

Here, we describe our experience in treating a patient with mediastinal hemangioma, a rare neoplasm. An abnormal shadow was noted in the thoracic region of a 54-year-old woman at a health checkup, and she was referred to our hospital. A neurogenic tumor was suspected based on the findings of the chest X-ray and computed tomography scan. Thoracoscopic tumorectomy was performed. The tumor surface was smooth with a reddish-dark reddish color, and capillary blood vessels showed marked growth around the tumor. The tumor was composed of medium or large blood vessels with a relatively thick vascular wall containing smooth muscle. On immunostaining, anti-CD34 antibody and Factor VIII were positive and D2-40 was negative. Based on these findings, the tumor was diagnosed as mediastinal venous hemangioma.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal, Murine-Derived
  • Antigens, CD34 / analysis
  • Biomarkers, Tumor / analysis
  • Factor VIII / analysis
  • Female
  • Hemangioma* / blood supply
  • Hemangioma* / chemistry
  • Hemangioma* / diagnosis
  • Hemangioma* / surgery
  • Humans
  • Immunohistochemistry
  • Mediastinal Neoplasms* / blood supply
  • Mediastinal Neoplasms* / chemistry
  • Mediastinal Neoplasms* / diagnosis
  • Mediastinal Neoplasms* / surgery
  • Middle Aged
  • Thoracoscopy
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Veins / pathology

Substances

  • Antibodies, Monoclonal, Murine-Derived
  • Antigens, CD34
  • Biomarkers, Tumor
  • monoclonal antibody D2-40
  • F8 protein, human
  • Factor VIII