[The analysis of detection rate of ambiguity of loci under HLA-typing by SSO technology]

Klin Lab Diagn. 2012 Apr:(4):29-32.
[Article in Russian]

Abstract

The article deals with the results of HLA-typing of 1829 patients on loci HLA-A, HLA-B, HLA-DRB1 using kits of LABType SSO reagents (One Lambada, USA). The indicators of each locus ambiguity are determined: locus HLA-A - 4.43%, locus HLA-B--4.43%, locus HLA-DRB1--0.16%. The list of "rare" alleles was applied to analyze 13 types of determined ambiguities on locus HLA-A, 27 types on locus HLA-B, 3 types on locus HLA-DRB1.

Publication types

  • English Abstract

MeSH terms

  • Alleles*
  • Female
  • Genetic Loci*
  • HLA Antigens / genetics*
  • Histocompatibility Testing / instrumentation
  • Histocompatibility Testing / methods*
  • Histocompatibility Testing / standards
  • Humans
  • Male
  • Reagent Kits, Diagnostic
  • Sequence Analysis, DNA / instrumentation
  • Sequence Analysis, DNA / methods*
  • Sequence Analysis, DNA / standards

Substances

  • HLA Antigens
  • Reagent Kits, Diagnostic