Health inequalities have become recently one of the major concerns of European health policy. Observed differences in health status of men and women are also frequently discussed within this framework, and are becoming a subject of growing interest of researchers. Clinical and epidemiological researches document male-female health differences, trying to explain them within bio-medical model. However, apart of biological (sex) divergence, health inequalities reflect differences in social roles, social status and culturally established patterns and stereotypes of femininity and masculinity (gender differences). The article, using sociological perspective, attempts to show that observed differences in man's and women's health may be attributable to the differing sociocultural and structural arrangements, social support and lifestyle factors of both genders. As a result, many of these differences are of inequality character. Another dimension of inequality discussed in this article is the way man and women are treated by the institution of medicine.