Massive haemoptysis in an intravenous drug user with infective tricuspid valve endocarditis

BMJ Case Rep. 2010 Aug 24:2010:bcr1020092404. doi: 10.1136/bcr.10.2009.2404.

Abstract

Major causes of morbidity in intravenous drug users are infections. In infective endocarditis, the tricuspid valve is mainly involved. Masses can cause septic embolisms and, in rare cases, they are associated with mycotic aneurysms of pulmonary arteries that lead to severe haemorrhage. We report the case of a young woman with a history of intravenous drug abuse and prolonged infective tricuspid valve endocarditis. Initially, echocardiography showed large masses on the anterior leaflet of the tricuspid valve and severe tricuspid regurgitation; blood cultures revealed staphylococcus and streptococcus species. Eight months after initial diagnosis, she presented with severe haemoptysis and fever. CT revealed a ruptured mycotic aneurysm of the right pulmonary artery. Lobectomy was performed immediately. Postoperatively, the patient fully recovered. After continued antibiotic treatment, follow-up examinations showed negative echocardiographic findings and blood cultures results.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aneurysm, Infected / diagnostic imaging
  • Aneurysm, Infected / etiology*
  • Aneurysm, Infected / surgery
  • Aneurysm, Ruptured / diagnostic imaging
  • Aneurysm, Ruptured / etiology*
  • Aneurysm, Ruptured / surgery
  • Anti-Bacterial Agents / therapeutic use
  • Echocardiography, Doppler / methods
  • Echocardiography, Transesophageal / methods
  • Endocarditis / diagnostic imaging
  • Endocarditis / drug therapy
  • Endocarditis / etiology*
  • Female
  • Follow-Up Studies
  • Hemoptysis / etiology*
  • Hemoptysis / physiopathology
  • Hemoptysis / therapy
  • Humans
  • Pneumonectomy / methods
  • Postoperative Care / methods
  • Pulmonary Artery / pathology
  • Pulmonary Artery / surgery
  • Risk Assessment
  • Staphylococcal Infections / diagnostic imaging
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / etiology
  • Substance Abuse, Intravenous / complications*
  • Substance Abuse, Intravenous / diagnosis
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Tricuspid Valve Insufficiency / diagnostic imaging
  • Tricuspid Valve Insufficiency / etiology*
  • Tricuspid Valve Insufficiency / surgery

Substances

  • Anti-Bacterial Agents