Abstract
Cushing syndrome is associated with significant morbidity and mortality if left untreated because of associated metabolic and cardiovascular complications. An extremely ill patient with Cushing's syndrome caused by adrenocorticotropic hormone producing pituitary macro adenoma responded dramatically to ketoconazole and cabergoline treatment. His 4 month long medical treatment resulted in improvement of hypercotisolism clinically and biochemically and in complete disappearance of pituitary macro adenoma without any surgical intervention.
MeSH terms
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14-alpha Demethylase Inhibitors / therapeutic use
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Adenoma / complications*
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Adenoma / diagnosis
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Adenoma / drug therapy
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Adult
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Antineoplastic Agents / therapeutic use
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Cabergoline
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Cushing Syndrome / drug therapy
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Cushing Syndrome / etiology*
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Diagnosis, Differential
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Drug Therapy, Combination
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Ergolines / therapeutic use*
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Humans
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Ketoconazole / therapeutic use*
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Magnetic Resonance Imaging
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Male
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Pituitary Neoplasms / complications*
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Pituitary Neoplasms / diagnosis
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Pituitary Neoplasms / drug therapy
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Severity of Illness Index
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Tomography, X-Ray Computed
Substances
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14-alpha Demethylase Inhibitors
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Antineoplastic Agents
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Ergolines
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Cabergoline
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Ketoconazole