Methods to determine antipathogenic potential of phenolic and flavonoid compounds against urinary pathogen Serratia marcescens

Angusamy Annapoorani; Radhakrishnan Parameswari; Shunmugiah Karutha Pandian; Arumugam Veera Ravi

doi:10.1016/j.mimet.2012.06.007

Methods to determine antipathogenic potential of phenolic and flavonoid compounds against urinary pathogen Serratia marcescens

J Microbiol Methods. 2012 Oct;91(1):208-11. doi: 10.1016/j.mimet.2012.06.007. Epub 2012 Jun 30.

Authors

Angusamy Annapoorani¹, Radhakrishnan Parameswari, Shunmugiah Karutha Pandian, Arumugam Veera Ravi

Affiliation

¹ Department of Biotechnology, Alagappa University, Karaikudi-630 003, Tamil Nadu, India.

PMID: 22759832
DOI: 10.1016/j.mimet.2012.06.007

Abstract

This study revealed the antipathogenic potential of natural compounds present in the edible fruits against urinary pathogen Serratia marcescens by using quorum sensing inhibition (QSI). The serum resistance assay was adopted to examine the immunomodulatory effects of QSI compounds to fight against bacterial infections.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Blood Bactericidal Activity
Flavonoids / isolation & purification
Flavonoids / pharmacology*
Fruit / chemistry
Humans
Phenols / isolation & purification
Phenols / pharmacology*
Quorum Sensing / drug effects*
Serratia marcescens / drug effects*
Serratia marcescens / isolation & purification
Serratia marcescens / pathogenicity
Serratia marcescens / physiology*
Urinary Tract Infections / microbiology
Virulence / drug effects

Substances

Anti-Bacterial Agents
Flavonoids
Phenols