The hitchhiker's guide to the role of (transient) hypoglycemia in refractory seizures and epilepsy

Pediatr Neurol. 2012 Aug;47(2):123-4. doi: 10.1016/j.pediatrneurol.2012.04.020.

Abstract

Hypoglycemia and hypoglycorrhachia, although they are uncommon causes of refractory seizures and epilepsy, should always be considered because they are potentially treatable conditions. A high index of suspicion and low threshold for testing recurrent blood and at least one cerebrospinal fluid glucose level are required. Jeavons syndrome and other refractory cryptogenic/idiopathic epilepsies may involve symptomatic etiologies, including hyperinsulinism, GLUT1 deficiency, and other metabolic disorders.

Publication types

  • Comment

MeSH terms

  • Epilepsy, Absence / complications*
  • Epilepsy, Absence / diagnosis*
  • Female
  • Humans
  • Hyperinsulinism / complications*
  • Hyperinsulinism / diagnosis*
  • Hypoglycemia / complications*
  • Hypoglycemia / diagnosis*

Supplementary concepts

  • Hyperinsulinemic hypoglycemia, familial, 6