Nanoemulsions as delivery systems for lipophilic drugs

J Nanosci Nanotechnol. 2012 Mar;12(3):2881-90. doi: 10.1166/jnn.2012.5690.

Abstract

Nanoemulsions have received a growing attention as colloidal drug carriers for pharmaceutical applications. Their advantages over conventional formulations include drug enhanced solubility and bioavailability, protection from toxicity, improved pharmacological activity and stability, more sustained delivery and protection from physical and chemical degradation. Nanoemulsions can be prepared by two major techniques, high-energy and low-energy emulsification. Both these emulsification methods have proved to be efficient to obtain stable nanoemulsions with small and highly uniform droplets. Further research into nanoemulsions is important to develop novel liquid formulations with more efficient results in therapeutic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / administration & dosage
  • Drug Delivery Systems*
  • Emulsions*
  • Kinetics
  • Nanotechnology*
  • Solubility

Substances

  • Anti-HIV Agents
  • Emulsions