Leydig cell tumor of the testis in tuberous sclerosis: lack of second hit events

Oncologist. 2012;17(7):927-9. doi: 10.1634/theoncologist.2012-0045. Epub 2012 Jun 15.

Abstract

This article presents the case of an adult patient with tuberous sclerosis complex who presented with large right benign and left malignant Leydig cell tumors. The tumors were examined to determine if they showed the classic hallmarks of TSC1/TSC2 involvement.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Humans
  • Leydig Cell Tumor / genetics
  • Leydig Cell Tumor / pathology*
  • Male
  • Testicular Neoplasms / genetics
  • Testicular Neoplasms / pathology*
  • Tuberous Sclerosis / genetics
  • Tuberous Sclerosis / pathology*