Abstract
This study presents the case of a 66-year-old man with a non-small cell bronchial carcinoma that metastasized into a prolactin (PRL)-producing pituitary adenoma. The pituitary adenoma cells were immunoreactive for PRL and vascular endothelial growth factor (VEGF). It is hypothesized that VEGF and PRL played a role in the development of metastasis within the adenoma.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Biomarkers, Tumor / metabolism
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Bronchial Neoplasms / metabolism
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Bronchial Neoplasms / pathology*
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Carcinoma, Non-Small-Cell Lung / metabolism
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Carcinoma, Non-Small-Cell Lung / secondary*
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Fatal Outcome
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Humans
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Male
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Pituitary Neoplasms / metabolism
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Pituitary Neoplasms / secondary*
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Prolactin / metabolism
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Prolactinoma / metabolism
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Prolactinoma / pathology*
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Vascular Endothelial Growth Factor A / metabolism
Substances
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Biomarkers, Tumor
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VEGFA protein, human
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Vascular Endothelial Growth Factor A
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Prolactin