Pulmonary affectation of vasculitis
Arch Bronconeumol. 2012 Nov;48(11):410-8.
doi: 10.1016/j.arbres.2012.04.007.
Epub 2012 Jun 6.
[Article in
English,
Spanish]
Affiliation
- 1 Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid, Spain.
Abstract
Respiratory tract affectation is frequent in some types of vasculitis, fundamentally in those associated with anti-neutrophil cytoplasmic antibodies (ANCA). The clinical, radiological and histopathological presentation is also heterogeneous and conditions the evolution. It is therefore necessary to establish an early diagnosis based on the symptoms because, thanks to new treatments, and despite them being potentially serious diseases, their prognosis has improved considerably in recent years. The present paper updates the diagnosis and the new therapeutic options for pulmonary vasculitis.
Copyright © 2012 SEPAR. Published by Elsevier España, S.L. All rights reserved.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / complications
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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / pathology
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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / therapy
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Antibodies, Monoclonal, Murine-Derived / therapeutic use
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Combined Modality Therapy
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Granuloma, Respiratory Tract / etiology
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Granuloma, Respiratory Tract / pathology
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Granulomatosis with Polyangiitis / complications
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Granulomatosis with Polyangiitis / pathology
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Granulomatosis with Polyangiitis / therapy
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Hemorrhage / etiology
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Humans
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Immunoglobulins, Intravenous / therapeutic use
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Immunosuppressive Agents / therapeutic use
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Lung / blood supply
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Lung Diseases / etiology*
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Lung Diseases / pathology
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Methotrexate / therapeutic use
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Plasmapheresis
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Rituximab
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Tumor Necrosis Factor-alpha / antagonists & inhibitors
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Vasculitis / classification
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Vasculitis / complications*
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Vasculitis / drug therapy
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Vasculitis / pathology
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Vasculitis / therapy
Substances
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Adrenal Cortex Hormones
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Antibodies, Monoclonal, Murine-Derived
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Immunoglobulins, Intravenous
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Immunosuppressive Agents
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Tumor Necrosis Factor-alpha
-
Rituximab
-
Methotrexate