2-Azabicyclo[2.2.1]hept-5-en-3-one: chemical profile of a versatile synthetic building block and its impact on the development of therapeutics

Chem Rev. 2012 Aug 8;112(8):4642-86. doi: 10.1021/cr2004822. Epub 2012 Jun 8.

Authors

Rohit Singh¹, Robert Vince

Affiliation

¹ Center for Drug Design, Academic Health Center, University of Minnesota, 516 Delaware Street Southeast, Minneapolis, MN 55455, United States.

PMID: 22681478
DOI: 10.1021/cr2004822

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Chemistry Techniques, Synthetic / methods*
Drug Design*
Humans
Lactams / chemical synthesis
Lactams / chemistry*
Lactams / pharmacology
Lactams / therapeutic use

Substances

Lactams
2-azabicyclo(2.2.1)hept-5-en-3-one