Kidney transplant ureteroneocystostomy: comparison of full-thickness vs. Lich-Gregoir techniques

Clin Transplant. 2012 Jul-Aug;26(4):E372-80. doi: 10.1111/j.1399-0012.2012.01655.x. Epub 2012 Jun 4.

Abstract

Despite a variety of urinary tract reconstructive techniques, urinary complications are the most frequent technical adverse event following kidney transplantation. We examined outcomes of two ureteroneocystostomy techniques, the full-thickness (FT) technique and the Lich-Gregoir (LG) technique in 634 consecutive kidney-alone transplants (327 FT and 307 LG) between December 2006 and December 2010. Urological complications at one yr post-transplantation occurred in 27 cases (4.3%) including 16 ureteral strictures (2.5%), four ureteral obstructions (0.6%) owing to donor-derived stones or intrinsic hematoma, and seven urine leaks (1.1%). Compared with LG, the FT technique was associated with similar proportions of ureteral complications overall (3.9% vs. 4.6%, p = 0.70), ureteral strictures (3.7% vs. 1.3%, p = 0.08), urinary stones/hematoma (1.0% vs. 0.3%, p = 0.36), and overall urinary leaks (1.6% vs. 0.6%, p = 0.22); however, the FT technique was associated with somewhat fewer urine leaks at the ureterovesical junction (0% vs. 1.3%, p = 0.05). There were no differences between the two groups in terms of length of stay, delayed graft function, urinary tract infection with the first post-transplant year, estimated glomerular filtration rate, and overall graft and patient survival. The FT technique of ureteroneocystostomy is technically simple to perform and has a similar incidence of urinary complications compared with the LG technique.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Case-Control Studies
  • Cystostomy / mortality*
  • Delayed Graft Function / epidemiology
  • Delayed Graft Function / etiology*
  • Delayed Graft Function / surgery
  • Female
  • Follow-Up Studies
  • Glomerular Filtration Rate
  • Graft Survival
  • Humans
  • Incidence
  • Kidney Diseases / complications*
  • Kidney Diseases / surgery
  • Kidney Transplantation / adverse effects*
  • Length of Stay
  • Male
  • Middle Aged
  • Prognosis
  • Survival Rate
  • Ureteral Diseases / epidemiology
  • Ureteral Diseases / etiology*
  • Ureteral Diseases / surgery
  • Ureterostomy / mortality*