The biochemiresistor: an ultrasensitive biosensor for small organic molecules

Leo M H Lai; Ian Y Goon; Kyloon Chuah; May Lim; Filip Braet; Rose Amal; J Justin Gooding

doi:10.1002/anie.201202350

The biochemiresistor: an ultrasensitive biosensor for small organic molecules

Angew Chem Int Ed Engl. 2012 Jun 25;51(26):6456-9. doi: 10.1002/anie.201202350. Epub 2012 May 25.

Authors

Leo M H Lai¹, Ian Y Goon, Kyloon Chuah, May Lim, Filip Braet, Rose Amal, J Justin Gooding

Affiliation

¹ School of Chemistry and the Australian Centre for NanoMedicine, University of New South Wales, Sydney, NSW 2052, Australia.

PMID: 22639391
DOI: 10.1002/anie.201202350

Abstract

New sensation: A resistance-based biosensor uses gold-coated magnetic nanoparticles (Au@MNPs) functionalized with the antibiotic enrofloxin (see picture; purple), which bind to anti-enrofloxin as analyte (blue). The Au@MNPs can be magnetically assembled between electrodes, and the measured resistance R is a function of analyte concentration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biosensing Techniques / methods*
Gold / chemistry*
Metal Nanoparticles / chemistry*
Models, Molecular
Organic Chemicals / analysis*

Substances

Organic Chemicals
Gold