The onchocerciasis chronicle: from the beginning to the end?

Andy Crump; Carlos M Morel; Satoshi Omura

doi:10.1016/j.pt.2012.04.005

The onchocerciasis chronicle: from the beginning to the end?

Trends Parasitol. 2012 Jul;28(7):280-8. doi: 10.1016/j.pt.2012.04.005. Epub 2012 May 25.

Authors

Andy Crump¹, Carlos M Morel, Satoshi Omura

Affiliation

¹ The Kitasato Institute and Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan.

PMID: 22633470
DOI: 10.1016/j.pt.2012.04.005

Abstract

The year 2012 marks the 25th anniversary of the donation of ivermectin to fight onchocerciasis and the projected date for elimination of transmission of the disease in the Americas. This review looks at the history of onchocerciasis, from its discovery through to 2025, by which time it is projected that the disease will have been eliminated as a public health problem, except in a handful of sub-Saharan countries, where it should be well on the way towards elimination.

Publication types

Historical Article
Review

MeSH terms

Animals
Delivery of Health Care / organization & administration
Disease Eradication / methods
Disease Eradication / organization & administration
History, 19th Century
History, 20th Century
History, 21st Century
Humans
Insect Control / methods
Ivermectin / therapeutic use*
Onchocerca / isolation & purification
Onchocerca / pathogenicity*
Onchocerca / physiology
Onchocerciasis / drug therapy
Onchocerciasis / epidemiology
Onchocerciasis / history
Onchocerciasis / prevention & control*
Simuliidae / drug effects
Simuliidae / parasitology

Substances

Ivermectin