Penetration resistance: PKR's other talent

Adam Lacy-Hulbert; Lynda M Stuart

doi:10.1016/j.immuni.2012.05.010

Penetration resistance: PKR's other talent

Immunity. 2012 May 25;36(5):695-6. doi: 10.1016/j.immuni.2012.05.010.

Authors

Adam Lacy-Hulbert¹, Lynda M Stuart

Affiliation

¹ Developmental Immunology/CCIB Massachusetts General Hospital/Harvard Medical School, Boston, MA 02144, USA.

PMID: 22633454
DOI: 10.1016/j.immuni.2012.05.010

Abstract

In this issue of Immunity, Irving et al. (2012) show that protein kinase R (PKR) regulates the cytoskeleton via an interaction with gelsolin. This alternative role for PKR prevents penetration of virions into the cell.

Publication types

Comment

Grants and funding

R01 AI079198/AI/NIAID NIH HHS/United States