Simplified rat lung transplantation using a new cuff technique

Taichiro Goto; Mitsutomo Kohno; Masaki Anraku; Takashi Ohtsuka; Yotaro Izumi; Hiroaki Nomori

doi:10.1016/j.athoracsur.2012.01.096

Simplified rat lung transplantation using a new cuff technique

Ann Thorac Surg. 2012 Jun;93(6):2078-80. doi: 10.1016/j.athoracsur.2012.01.096.

Authors

Taichiro Goto¹, Mitsutomo Kohno, Masaki Anraku, Takashi Ohtsuka, Yotaro Izumi, Hiroaki Nomori

Affiliation

¹ Department of General Thoracic Surgery, School of Medicine, Keio University, Tokyo, Japan. taichiro@1997.jukuin.keio.ac.jp

PMID: 22632516
DOI: 10.1016/j.athoracsur.2012.01.096

Abstract

We introduce a new procedure for orthotopic left lung transplantation in rats. First, cuffs are attached to vessels or bronchi in both donors and recipients. Next, the cuffs are anastomosed by interposing pieces of the donor's descending aorta. Anastomosis time is markedly reduced to approximately 10 minutes. Transplantations were completed in 8 rats without technical errors. This rat lung transplantation technique is a straightforward method any surgeon can perform.

MeSH terms

Anastomosis, Surgical / methods*
Animals
Aorta / surgery*
Blood Vessel Prosthesis*
Bronchi / surgery*
Catheters*
Lung / blood supply*
Lung Transplantation / methods*
Male
Microsurgery / methods
Pulmonary Artery / surgery*
Pulmonary Veins / surgery*
Rats
Rats, Inbred Lew