A novel porcine circovirus type 2a strain, 10JS-2, with eleven-nucleotide insertions in the origin of genome replication

Lin Cai; Xue Han; Dongmei Hu; Xiaoxia Li; Baoyue Wang; Jianqiang Ni; Zhi Zhou; Xiuling Yu; Xinyan Zhai; Kegong Tian

doi:10.1128/JVI.00760-12

A novel porcine circovirus type 2a strain, 10JS-2, with eleven-nucleotide insertions in the origin of genome replication

J Virol. 2012 Jun;86(12):7017. doi: 10.1128/JVI.00760-12.

Authors

Lin Cai¹, Xue Han, Dongmei Hu, Xiaoxia Li, Baoyue Wang, Jianqiang Ni, Zhi Zhou, Xiuling Yu, Xinyan Zhai, Kegong Tian

Affiliation

¹ Veterinary Diagnostic Lab, China Animal Disease Control Center, Beijing, People's Republic of China.

Abstract

Here, we report a novel porcine circovirus type 2a (PCV2a) strain with 11 nucleotides (nt) inserted in the origin of genome replication (Ori). This is the first report of a PCV2a strain with nucleotide insertion in Ori. Our study will help further epidemiological studies and extend our knowledge of evolutionary characteristics of PCV2.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Base Sequence
Circoviridae Infections / veterinary*
Circoviridae Infections / virology
Circovirus / classification
Circovirus / genetics
Circovirus / isolation & purification*
DNA Replication
Genome, Viral*
Molecular Sequence Data
Mutagenesis, Insertional*
Phylogeny
Swine
Swine Diseases / virology*

Associated data

GENBANK/JQ806749