In vitro activities of ceftobiprole, dalbavancin, daptomycin, linezolid, and tigecycline against methicillin-resistant Staphylococcus aureus blood isolates: stratified analysis by vancomycin MIC

Yong Pil Chong; Su-Jin Park; Hee Sueng Kim; Eun Sil Kim; Mi-Na Kim; Sung-Han Kim; Sang-Oh Lee; Sang-Ho Choi; Jin-Yong Jeong; Jun Hee Woo; Yang Soo Kim

doi:10.1016/j.diagmicrobio.2012.01.015

In vitro activities of ceftobiprole, dalbavancin, daptomycin, linezolid, and tigecycline against methicillin-resistant Staphylococcus aureus blood isolates: stratified analysis by vancomycin MIC

Diagn Microbiol Infect Dis. 2012 Jul;73(3):264-6. doi: 10.1016/j.diagmicrobio.2012.01.015. Epub 2012 May 22.

Authors

Yong Pil Chong¹, Su-Jin Park, Hee Sueng Kim, Eun Sil Kim, Mi-Na Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Jin-Yong Jeong, Jun Hee Woo, Yang Soo Kim

Affiliation

¹ Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

PMID: 22621914
DOI: 10.1016/j.diagmicrobio.2012.01.015

Abstract

The in vitro activities of newer agents against 569 methicillin-resistant Staphylococcus aureus (MRSA) blood isolates stratified by vancomycin MIC values (≤1 versus >1 μg/mL) were evaluated using broth microdilution methods. All agents had good in vitro activities against MRSA regardless of vancomycin MIC values. Some significant correlations between vancomycin and newer agents' MIC values were observed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Bacteremia / microbiology*
Humans
Methicillin-Resistant Staphylococcus aureus / drug effects
Methicillin-Resistant Staphylococcus aureus / isolation & purification
Microbial Sensitivity Tests
Staphylococcal Infections / microbiology*

Substances

Anti-Bacterial Agents